The offensive line
Left tackle Nate Solder has improved as the season has progressed. With All-Pro right tackle Marcus Cannon placed on injured reserve the Patriots turned to LaAdrian Waddle. He played well but was injured against Miami and returned to the field for a few series last week in Pittsburgh. He was replaced by Cameron Fleming at right tackle who was solid but hardly dominant.
The Bills are 29th in the NFL in sacks (per ESPN.com) with just 24 sacks in 14 games and veteran defensive tackle Kyle Williams (two sacks) is questionable to play. Buffalo’s edge rushers Shaq Lawson (four sacks), Jerry Hughes (three sacks) and Lorenzo Alexander (three sacks) have struggled to get to the quarterback.
Buffalo wants to pressure Brady with just three or four rushers and flood the short passing lanes with linebackers while the corners and safeties stay in their cover-two scheme.
If the pass rush does not get to Brady that is when holes will open up in the cover-two for Brady to exploit down the field. New England will need Fleming and Thuney to hold-up as the Bills–who have pressured nobody this season–were able to pressure quarterback Tom Brady in the last match-up in Buffalo (three sacks and five quarterback hits).